Research Associate II / Senior Research Associate I LNP Delivery - Immunology & NGS workflow

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Job description

Who We Are:

ReCode Therapeutics is a clinical-stage genetic medicines company using precision delivery to power the next wave of mRNA and gene correction therapeutics. ReCode's proprietary Selective Organ Targeting (SORT) lipid nanoparticle (LNP) platform enables highly precise and targeted delivery of genetic medicines directly to the organs, tissues and cells implicated in disease, enabling improved efficacy and potency. ReCode's lead programs include RCT1100 for the treatment of primary ciliary dyskinesia caused by pathogenic mutations in the DNAI1 gene, and RCT2100 for the treatment of the 10-13% of cystic fibrosis patients who have Class I mutations in the CFTR gene and do not respond to currently approved CFTR modulators. RCT1100 and RCT2100 are inhaled disease-modifying mRNA-based therapies formulated using the SORT LNP delivery platform. ReCode is expanding its pipeline to develop potential therapies for other rare and common genetic diseases, including musculoskeletal, central nervous system, liver and infectious disease indications.

Summary of Position:

We are seeking a motivated and detail-oriented researcher to join our dynamic team. In this role, you will focus on performing a variety of in vitro assays to screen and characterize new lipid nanoparticle (LNP) formulations for therapeutic applications. You will be supporting a team of research scientists and research associates in the development of ReCode's proprietary LNP solutions. This is a contract position based in Menlo Park, CA.

Responsibilities:

• Perform routine cytokine assay and analysis in cultured human peripheral blood mononuclear cells (PBMCs).
• Execute next-generation sequencing-based experiments, including sample preparation from cells and tissues, and data analysis.
• Potential stretch goal to work on new high-content/image-based screening.
• Ensure site-wide electronic lab notebook and record keeping complies with company policies.

Qualifications:

• Bachelor's or Master's degree in molecular biology, cell biology, or a related discipline with 2+ years of relevant industry experience. Familiarity with non-viral delivery platforms is preferred but not required.
• Demonstrated proficiency in multiplex immune assays (e.g., MSD, Luminex) is essential. Flow Cytometry experience is preferred.
• Experience in Molecular Biology Assays (e.g. mRNA tissue extraction, qPCR, NGS) and Cell Biology Assays (e.g., immunofluorescence, cell imaging, microscopy) and data analysis software (GraphPad Prism, Flowjo, Fiji) preferred, but not necessary.
• Ability to maintain accurate and well-organized laboratory records.
• Strong analytical, troubleshooting, and problem-solving skills.
• Desire to work in a fast-paced environment and contribute to progressing our LNP franchise.

Salary Range: $45-$60/hr

Benefits Offered for Full-Time Employees:

• No premium cost for employees - 100% subsidized by ReCode for full-time employees
• Company 401k contribution
• 15 days of company paid holidays, including a holiday shutdown (usually the last week of the year)
• Mental health support for employees & their families
• FSA available, including a lifestyle spending account subsidized by company
• Employee discounts at hotspots

ReCode Therapeutics () offers a competitive compensation/benefits package with a friendly, collaborative culture that values employee engagement and ongoing career development.

ReCode Therapeutics is an Equal Opportunity Employer.

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