Postdoctoral Scientist - Antibody-enabled Membrane Protein Discovery

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Job description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

We are seeking a highly motivated and talented Postdoctoral Scientist to join our dynamic team at the Lilly Biotechnology Center in San Diego, CA. The successful candidate will play a key role in our antibody-enabled membrane protein discovery projects. This position offers an exciting opportunity to work on groundbreaking research and contribute to the development of novel therapeutic strategies.

Responsibilities:

• Design and execute experiments to discover and engineer antibodies to biologically relevant conformations of membrane proteins.

• Develop and optimize novel protocols for antibody generation, screening, and validation.

• Collaborate with cross-functional teams to integrate findings into broader research projects.

• Analyze and interpret experimental data and present findings at internal and external meetings.

• Prepare manuscripts for publication in peer-reviewed journals.

Basic Requirements:

• Ph.D. in Molecular Biology, Biochemistry, or a related field.

• Strong background in antibody technology and membrane protein biology such as GPCRs.

• Experience in protein engineering and characterization.

• Experience with techniques such as protein expression, purification, and characterization.

• Proficiency in data analysis and interpretation.

• Excellent communication and teamwork skills.

Additional Skills/Preferences:

• Experience with display technologies (e.g., phage display, yeast display, or mammalian display).

• Experience with flow cytometry and fluorescence-activated cell sorting (FACS).

• Excellent communication and teamwork skills.

• Experience of cell-based assay for GPCR targets.

• The successful candidate must be available to start latest by January 2025.

About Eli Lilly's Postdoctoral Scientist Program

When it comes to research and development, our goal is to discover and deliver innovative medicines that make life better for people around the world. It's challenging, expensive, and often filled with failure. But even when we fail, we advance medical science and understanding by learning more about diseases, biology, and chemistry - ultimately bringing new solutions one step closer to reality.

Over the course of our history, we have shed light on some of the toughest health care problems known to man - diabetes, heart disease, infectious diseases, neuroscience disorders, cancer, and more. We could not pursue this without our research and development team.

Postdoctoral scientists help us continue this pursuit. During your experience you will get:

• Top industry research experience

• Mentoring by some of Lilly's top scientists

• Laboratory and classroom training and education to further your development

• Collaboration and networking across dozens of postdoctoral scientists and other researchers

Additional Information

• This position is not permanent. It is for a fixed duration of two years with potential to extend to 3 years. You will have opportunities to apply for full time positions after your duration is complete.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups.

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