Technical Development Scientist II

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Job description

Job Title: Technical Development Scientist II

Job Location: 1 Dna Way, South San Francisco, CA 94080

Job Type: Contract

Contract Duration: 12 Months

Contract with possible extension depending on business need and performance.

Payrate is $ 62.11/HR on W2

Job Knowledge & Scope:

RMG, in the Cell Culture and Bioprocess Operations department, is responsible for providing support to pre-Early Stage Research to Early Development projects with high-throughput protein production from mammalian transient cultures. We are looking for a motivated candidate with cell culture and sterile technique experience to join our team to enable protein production at and help advance our portfolio.

Key Responsibilities

Perform transient transfections in CHO and HEK293 cells in scales 1mL to 25L to support

pipeline productions adhering to established protocols

Maintain seed train cell cultures in bioreactors and shake flasks

Operate liquid handlers - Tecan and Hamilton for automated processes

Operate wave bag reactors for productions and cell maintenance

Maintain and troubleshoot key cell culture instruments such as Vi-Cell, Nova Flex2, Nova Flex, Cedex and bioreactors

Participate in troubleshooting production or platform processes

Participate in lab management and data management.

Contribute to improving existing cell culture platforms and developing new platforms to deliver diverse protein and cellular reagents to enable a large number of research programs.

The candidate must be highly self-motivated, organized, detail oriented and responsive to feedback. The candidate is expected to precisely follow written procedures, practice sterile technique, demonstrate accurate documentation skills, and report deviations in a timely manner. They should be able to work independently within guidelines and policies, with minimal guidance.

Qualifications Required:

PhD (with 0-2yrs relevant experience) in Biotechnology, Chemistry, Biochemistry or related fields

Suspension adapted mammalian cell culture (CHO and/or HEK293)

Excellent written and verbal communication skills, and have strong collaborative skills.

Preferred

State-of-the-art transient and stable protein expression experience

Relevant bioreactor experience

Hands-on experience with automation and liquid handlers like Tecan Freedom Evo and Hamilton Microlab Star

Knowledge of cell biology, cell engineering, molecular biology, recombinant protein

purification and protein characterization is preferred

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