Principal Research Scientist I, Analytical R&D (LAI)

---

Job description

Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . on Twitter , Facebook , Instagram , YouTube and LinkedIn .

Job Description
We are seeking a highly motivated, experienced analytical scientist to impact early phase development of New Chemical Entities (NCEs) in both drug substance and drug product throughout the preclinical and clinical lifecycle. This role will focus specifically on the analytical development of long-acting injectable (LAI) delivery systems. In relation to LAIs, the candidate should have expertise in applying general analytical principles and regulatory guidelines within an R&D environment. The candidate will need experience in analytical control strategies, analytical method development, characterization, validation, release, and stability testing.

He/ She should be able to direct research and/or project activities by effectively mentoring, guiding and/or supervising scientific personnel. Should conceive, execute and communicate novel multi-disciplinary research or development strategies that achieve project and strategic goals. Serve as a lead scientist on projects and contribute scientific insights into multiple other projects and initiatives.

He/she must foster productive collaborations within the global Analytical R&D organization and with R&D cross-functional partners such as Pre-Clinical Safety, Process Chemistry, Process Engineering, Drug Product Development, and Quality Assurance and Regulatory Affairs.

• Serve as the lead analytical scientist on the development of long-acting injectable (LAI) delivery systems.
• Utilize in-depth understanding of a wide range of analytical techniques to conduct research and development studies related to the development of LAIs.
• Method development, testing procedures, and implementation of analytical control strategies to help the advancement of drug discovery candidates.
• Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies.
• Routinely demonstrate scientific initiative and creativity in research or development activities and maintain a high level of productivity in the lab.
• Generate new scientific proposals related to LAIs and lead those efforts.
• May mentor/supervise a team to support the development of NCE candidates (RSM to API to DP) from pre-clinical through Phase II clinical trials and be accountable for the effective performance of the team/individuals.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.
• Encourage ideas and drive for continuous improvement and champion initiatives within Analytical R&D and across R&D partner functions.
• Understand and comply with AbbVie safety, quality and regulatory policies and government regulations.

Qualifications

• Bachelors, Masters, or Ph.D. in Pharmaceutic Chemistry, Analytical Chemistry, or related field, typically with a minimum of 14 (BS), 12 (MS), or 6 (Ph.D.) years relevant industry experience in development of LAIs.
• Demonstrated track record in the analytical development of injectable products.
• Strong technical background in analytical chemistry, excellent analytical problem-solving skills. Capable of independently developing and troubleshoot analytical methods.
• Demonstrate creative 'out of the box' thinking to solve difficult problems and
• Champion new technologies to achieve project goals.
• In-depth experience with development of dissolution methods.
• Hands on experience with HPLC analysis and method development along with fundamental understanding and working knowledge of various analytical techniques including MS, GC, ICP-OES, IC, and NMR.
• Self-motivated, hard-working, detail-oriented individual able to work in a fast-paced team environment.
• High-quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers.

Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• On-site position located in North Chicago
• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible to participate in our short-term incentiveprograms.
• This job is eligible to participate in our long-term incentiveprograms

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

<!– job description page –>