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Scientist, In Vivo

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AstraZeneca PLC

2024-09-20 12:46:50

Job location Gaithersburg, Maryland, United States

Job type: fulltime

Job industry: Science & Technology

Job description

Scientist, In Vivo Gaithersburg, MD Join our Clinical Immuno-Oncology Discovery group in the Early Oncology department in Gaithersburg, Maryland. We are seeking a highly motivated, in vivo-based scientist with a background in cancer immunology. As a key member of our team, you will support innovative bioscience research of clinically staged therapeutics of cancer. You will develop and execute murine studies to assess the function of our candidate drugs and dissect the mechanism of action of novel therapeutics targeting the immune system. This position will be primarily in vivo focused and may also include in vitro and ex vivo evaluations to dissect immune cell modulation. Accountabilities: You will be responsible for developing and performing murine studies, analyzing data, interpreting results independently, and maintaining appropriate documentation. You will also be expected to work well within a team and communicate effectively both orally and in writing. Essential Skills/Experience: Bachelor's Degree in Biology or related field with 3+ years of relevant experience or Master's Degree in Immunology, Cancer Biology, Cell Biology or related field with 0-3 years of relevant experience Impeccable aseptic technique, with knowledge of cell line culturing & passaging Strong in vivo skills- mouse handling, tumor implantation (sq, orthotopic), drug administration (IP, SQ, IV, PO), blood collection & necropsy Ability to make detailed observations, analyze data, and interpret results independently Preparation of precise technical summaries, protocols, quantitative analyses, and maintenance of appropriate documentation Team player who is well organized with strong interpersonal skills and excellent oral and written communication skills Willingness to perform in vivo murine models Desirable Skills/Experience: Previous experience in Immuno-Oncology and knowledge of immune based assays or endpoints would be preferred Experience with humanized mouse models preferred but not required. Ability to independently perform multi-color flow cytometry, or have strong interest to learn About AZ Oncology At AstraZeneca's Oncology R&D department, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. We are united in our vision to eliminate cancer as a cause of death. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. We lead through true collaboration, building collective wisdom by giving everyone a chance to input. It's science with an impact-making a difference for patients and people around the world. About Our Gaithersburg Oncology Hub Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration. The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams. So, what's next? Are you ready to take our leading Oncology pipeline to the next level? Apply now to join our team! If you're curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner. Closing Date: September 20, 2024 Competitive remuneration and benefits apply We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package. Where can I find out more- Our Social Media, Follow AstraZeneca on LinkedIn Follow AstraZeneca on Facebook Follow AstraZeneca on Instagram AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Date Posted 23-Aug-2024 Closing Date 19-Sep-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

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