Scientist - Cochlear Histology

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Job description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

The Early Preclinical Development (EPD) Team is seeking an Associate Scientist with experience in inner ear histology to support discovery and IND-enabling animal studies. The ideal candidate will have experience in histologic techniques specific to the inner ear, such as microdissection of the mouse and non-human primate (NHP) inner ear tissues into discrete anatomical regions, and further processing of these tissues using various histologic techniques, in addition to imaging, analysis, and preparation of data for presentation. Cross-functional work may be required to advance Company goals. The successful candidate will be self-motivated and creative, with a desire to succeed at the highest level in a highly collaborative and fast-paced environment.

Job Responsibilities:

• Perform mouse and NHP inner ear microdissections

• Perform NHP temporal bone extraction and processing

• Prepare inner ear tissues for embedding and preparation for frozen sections

• Preparation of inner ear tissues for molecular analyses

• Perform immunohistochemistry

• Perform epifluorescent imaging, cochlear frequency mapping, and confocal microscopy

• Produce graphs and charts from histologic data

• Preparation of histologic images for presentation

• Development and/or review of immunohistochemistry protocols and image acquisition strategies

• Inventory ordering and database management

• Collaborate closely with cross-functional teams and external groups to coordinate execution of complex studies

• Identify and communicate potential efficiencies for day-to-day operations

• Weekend work may be required at times

Basic Qualifications:

• Bachelor's Degree with 0+ years of experience, hands-on experience with inner ear biology is preferred.

Additional Skills and Preferences:

• Experience in solving scientific problems and/or image analysis using programming languages

• Experience and programming skills in at least one language such as Python or MATLAB

• Knowledge of cochlear anatomy, cochlear microdissection (whole-mount and sections), and methods for histological preparation of inner ear tissues required

• Experience with modern imaging techniques; epifluorescent and confocal microscopy required

• Excellent computer skills; proficiency in Microsoft Office (Word, Excel, Teams, PowerPoint, Outlook, Adobe Suite)

• Experience with image analysis software (ImageJ, Amira, LasX, Imaris); may include coding

• Excellent laboratory technical lab skills (pipetting, reagent preparation, liquid handling)

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups.

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