Senior Research Associate

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Job description

Roles & Responsibilities:

Independently plan, execute, analyze, and interpret in vitro and in vivo immunological assays that support the initiation and/or advancement of drug candidate projects

Proactively evaluate new technologies and develop new assays to accelerate early-stage

discovery activities and/or enhance our understanding of disease mechanisms

Manage multiple projects simultaneously and work cross-functionally with colleagues in the oncology, protein engineering, chemistry, translational medicine, biomarker and clinical groups

Presents research findings and recommendations to senior staff and contribute to

preparation of research reports, manuscripts, INDs, and patent filings

Education & Experience:

Master's degree with 3+ years of experience, or Bachelor's degree with 5+ years of

experience in immunology, immuno-oncology, cell biology, molecular biology, or

biochemistry in industry or academia.

Direct experience in research drug discovery and target identification/validation in oncology

or immuno-oncology is highly desirable.

Strong understanding of immune cell biology, including T cell and myeloid cells.

Proficiency in primary T-cell-based functional assays such as activation, proliferation and

cytotoxicity.

Experience in conducting and optimizing cell-based assays, as well as performing studies

to assess immune responses in human and animal models (including whole blood, PBMCs,

and various primary cell subsets).

Hands-on experience in general molecular and cell biology methods, including mammalian cell culture, multi-color flow cytometry, western blot, ELISA/Luminex/MSD, and CRISPR

technology.

Attention to detail with excellent organizational and record keeping skills is a requirement

Excellent communication and interpersonal skills are required.

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