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Senior Associate Scientist- Oligonucleotide Chemistry (Synthesis and Conjugation)

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Regeneron Pharmaceuticals, Inc.

2024-11-18 22:48:13

Job location Hawthorne, New York, United States

Job type: fulltime

Job industry: Science & Technology

Job description

We are seeking a highly motivated Senior Associate Scientist to advance our pipeline of targeted oligonucleotide therapeutics as a part of Regeneron Genetics Medicine (RGM). You will be a key contributor toward the design, generation & physicochemical characterization of bioconjugates for delivery of oligonucleotides.

As a Senior Associate Scientist, a typical day might include the following:

  • Planning and running experiments for synthesis, purification, and characterization of oligos and oligo-conjugates

  • Generating oligo conjugates by applying both well-established and novel conjugation chemistries.

  • Optimizing and developing robust processes to increase synthesis and conjugation throughput

  • Accurately documenting results in electronic notebook and present results in team meetings

  • Working successfully in a cross-functional team both independently and as a teammate

The job might be for you if you:

  • Enjoy working in a laboratory-based role with strong support for skill and career development

  • Are detail-oriented with strong organizational skills

  • Exhibit flexibility with changing priorities and can effectively manage multiple projects

  • Have excellent verbal and written communication skills

In order to be considered for this role, you must have at least BS/MS in Biochemistry, Chemistry, or related field and 3-5+ years of relevant experience. Industry experience is preferred. We need someone with proficiency in synthesis of oligos and/or oligo conjugates. Experience working with protein purification using AKTA systems is desired. In addition, experience with analytical characterization of antibodies, oligonucleotides, and conjugates using HPLC or mass spectrometry is desired.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)

$77,600.00 - $126,600.00

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