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Post Doctoral Scientist - Childhood Cancer

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Nationwide Children's Hospital

2024-09-21 00:38:30

Job location Columbus, Ohio, United States

Job type: fulltime

Job industry: Science & Technology

Job description

Overview We are seeking a Post-Doctoral Scientist - A postdoctoral position is available immediately for a scientist with experience in molecular and/or cancer biology. The Chandler lab is investigating the link between alternative splicing and cancer, including pediatric sarcomas and hepatocellular carcinoma. The appointee will investigate molecular mechanisms involved in the induction of alternative splicing in response to cancer promoting stimuli as well as the downstream effects of splicing changes. Cell culture, in vitro splicing and mouse models serve as systems in which to study the mechanism for alternative splicing as well as the biological endpoints of the pathways. The laboratory's approaches include integration of cell biology, molecular biology, genetics, and biochemistry. Chandler Lab Nationwide Children's Hospital (nationwidechildrens.org) Responsibilities What Will You Be Doing? Expertise in molecular biology, genetics, and/or biochemistry is preferred. Experience in RNA processing is desirable. The successful candidate will confer regularly with the principal investigator but must incorporate self-directed research, excellent technical, presentation, and communication skills as essential parts of the job. The candidate will be expected to co-publish scientific articles in appropriate refereed journals, and to work toward the goal of becoming independent in his/her research effort and obtaining external research funding. Qualifications What We Are Looking For? Candidates should have a Ph.D. or MD/PhD in cell biology, cancer biology, molecular biology, or biochemistry. Knowledge and expertise in mouse handling is preferred. Demonstrate firm foundation in basic scientific principles, reproduce and/or develop assays to meet experimental needs, possess good hands in the lab. Interpret experimental data, troubleshoot protocols and adjust experimental design based on preliminary results. Communicate her/his thoughts well and keeps clear record of her/his experiments. In addition to her/his technical skills and good work ethic, be able to design and interpret experiments with minimal guidance.

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